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huang qin 黃芩 (in English and Chinese

by: Joe Hing Kwok Chu

 

Pharmaceutical name:

英文藥 名 :

Radix Scutellariae Baicalensis

Biological name:

拉丁名 :

  1. Scutellaria baicalensis Georgi.

  2. S. amoena C.H. Wright (in Southern part of China)

  3. S. viscidula Gge. ( in northeastern China)

Pron. in Japanese:

日語發 音 :

egon

Pron. in Korean:

韓語發 音 :

kwanggum

Pron. in Cantonese:

粵語發 音 :

wong4 kam4

Common Name:

英文名 :

baiscal skullcap root, scutellaria, scute

 Other Name:

別名:

shan cha gen 山茶根,huang qin cha 黃芩茶,tu jin cha gen 土金茶根,tiao qin 條芩,ku qin 枯芩

Distribution:

Hebei, Henan, Shanxi, Shandong, Inner Mongolia, Liaoning, Jilin

Properties (characteristics)﹕

性味﹕

bitter,  cold

苦﹐寒

Channels (meridians) entered:

歸經﹕

gallbladder, large intestine, lung, stomach

膽﹐大腸﹐肺 ﹐胃

Actions & Indications:

主治:

clears damp-heat and dries fire, stops bleeding, calms fetus, lower liver fire , for jaundice,  hypertension , anxiety, headache due to cold or flu, prostate Cancer, breast cancer,  red eyes and sore throat,  cough and asthma due to heat syndromes.

 濕熱  ﹐止血,安胎,降陽之,治煩躁不安,血壓高 前列腺癌, 乳癰,風 熱 濕 熱 頭 痛 , 熱 嗽 喉 腥 , 定 喘 嗽 , 黃 疸 , 血 熱 , 吐血,鼻衄, 崩 漏,目赤腫痛 ,乳癰 ,一般癌症 。

Medical

Function:

藥理﹕

Medical Function:

1. effects on digestive system: alcohol extract of huang qin or its ingredient baicalin can promote secretion of bile but another ingredient wogonin does not have this effect. Baicalein can promote movements of extra body intestines of rabbits but wogonin does not have this effect. Huang qin possesses a mild diarrhea effect.

2. anti - histamine effect: alkaloids of huang qin possesses antihistamine effect. It can inhibit edema of rats caused by carrageenin.

3. anti allergenic effect: alcohol extract of huang qin inhibits acute asthma attack and allergenic eczema. Baicalein has anti-toxin effect,  inhibits permeability of capillaries and anti acetylcholine and anti anaphylaxis effects.

4. broad spectrum antibiotic effect

5. prevents atherosclerosis

6. blood thinning effect: one of the ingredients, Oroxylin A, can  promote an enzyme to produce nitrogen oxide, a potential for stroke and myocardiac infarction therapy.

7. anti hepatitis B virus [1]

藥理﹕

一 . 對 消 化 系 統 影 響 : 本 品 醇 抽 取 物 或 其

成 份 黃芩苷 ( baicalin )有 促 進 膽 汁 分 泌 作 用 , 

另 一 成份 漢黃芩素 ( wogonin ) 無 此 作 用 。

黃 芩 素 ( baicalein ) 對 兔 離 體 腸 管 具 有 運 動

亢 進 作 用 , 但 漢 黃 芩 素 無 此 作 用 。 黃 芩

具 有 緩 瀉 作 用 。

二 . 抗 炎 症 作 用:  黃 芩鹼 素 類 , 有 抗 炎 症

作 用 , 對 大 白 鼠 因 卡拉膠(carrageenin) 引 起 浮 腫 有 顯 著 抑 制 作 用 。

三 . 抗 過 敏 作 用 :

黃 芩 醇 抽 取 物 抗 過 敏 作 用 , 對 急 性 氣 喘 及

過 敏 性 皮 膚 炎 有 抑 制 效 果 。 黃 芩 素 有 解

毒 作 用 , 抑 制 毛 細 血 管 透 過 性 作 用 , 抗 乙

醯 膽 素 (acetylcholine) 作 用 及 抗 全身型過敏性反應(anaphylaxis) 作 用 。

四 . 廣 譜 抗 菌 作 用 :

 本 品 濃 液 , 在 試 管 內 對 革 蘭

氏 陽 性 菌 有 抑 制 作 用 。

五 . 防 止 粥 狀 動 脈 硬 化 作 用:

本 品 水 浸 液 , 連 續 經 口 給 藥 , 對 兔 實 驗 性

誘 發 之 粥 狀 動 脈 硬 化 症 有 預 防 作 用 。

六.  治療腦中風及心肌梗塞等血管病﹕

成分千層紙素A(Oroxylin A),用以抑制誘導性 一氧化氮製造酵素,具治療腦中風及心

肌梗塞等血管病的潛能。

七. 抗乙型肝炎病毒[1]

Chemical ingredients:

化學成 分:

Chemical ingredients:

1.(1) (baicalein)1,2,(baicalin)3, (5,6-dihydroxy-7-O-glucoside-flavone)4, (chrysin)5, (5, 7, 2'-trihydroxy-flavone)4,6, (5, 7, 2', 3'-tetraflavone)6,7, (5, 7, 2', 6'-tetraflavone)6, 8, (5, 7, 2'-trihydroxy-8-methoxyflavone)1, (oroxylin-A), (oroxylin-A-glucoronide)3, (5, 7, 2'-trihydroxy-6-methoxyflavone)2, 9, (nor-wogonin)9, (5, 8, 2'-trihydroxy-7-methoxyflavone)5, (Wogonin)10, *-methoxy-5-O-glucoside flavone)11, (8-methoxy-5-O-glucoside flavone)11, (Wogonoside)3, 5, 7, 2' (Scutevulin) 4,6,  (5, 7, 4'-trihydroxy-8-methoxy flavone)2,8, (5, 7, 2'-trihydroxy-8, 6'-dimethoxy- flavone)4, (5, 7, 2', 5'-tetrahydroxy-8, 6'-dimethoxy flavone)4,12, (5-hydroxy-7, 8-dimethoxyflavone)9, (skullcapflavone I), (skullcapflavone II)13,14, (5, 2', 6'-trihydroxy-7, 8, -dimethoxy flavone)7, (5, 7, 4'-trihydroxy-6-C-glucoside-8-C-arabinoside flavone)15, (5, 7-dihydroxy-6, 8, 2', 3'-tetramethoxy-flavone)16, (5, 8-dihydroxy-6, 7-dimethoxyflavone)6,8, (5, 8, 2'-trihydroxy-6, 7-dimethoxyflavone)5, (5, 2'-dihydroxy-6, 7, 8-trimethoxyflavone)6,9, (5, 2', 5'-trihydroxy-6, 7, 8-trimethoxyflavone)4,6.

(2) (7,2', 6'-trihydroxy-5-methoxyflavanone)7, (dihydro baicalin)9, (dihydrooroxylin-A)9, (5,7, 4'-trihydroxy-6-methoxyflavanone)2,5.

(3) (7, 2', 6'-trihydroxy-5methoxychalcone)7, (2, 6, 2', 4'-tetrahydroxy-6'-methoxychalcone)7.

(4) (3, 5, 7, 2', 6'-pentahydroxy flavononol)11.

(5) (3, 5, 7, 2', 6'-pentahydroxyflavonol)7.

2. [2-(3-hydroxy-4-methoxyphenyl) - ethyl-1-O-α-L-rhamnostl-(1-->3)-β-D- (4-ferulo-yl) -glucoside]15.

3. (proline)

4. (acetophenone), [(E) -4-phenyl-3-buten-2-one], (1-phenyl-1, 3-butanedion), (palmitic acid, (oleic acid)17.

5. (glucose), (sucrose), Camphestrol, (stigmasterol), (sitosterol)3, 14, 16.

 

Dosage:

用量:

6 to 15 g

 3~15 克。

Samples of formulae:

處方舉例:

long dan xie gan tangxiao xu ming tang,   xiao chai hu tang, e jiao huang qin tang

 龍 膽瀉肝湯, 小續命湯, 小柴胡湯阿 膠黃芩湯。

Modern Research:

 to be loaded.

Cautions:

禁 忌 ﹕

not to use in case of  pixu (spleen deficient) with weak digestion. Avoid using huang qin while on blood thinning medication.

脾 虛 ,少食,便溏者忌服。用抗凝藥時 須避免同時用黃芩。

[1] J Viral Hepat. 2013;20(7):445-452. 

carrageenin : Any of a group of closely related colloids derived from Irish moss and several other red algae, widely used as a thickening, stabilizing, emulsifying, or suspending agent in industrial, pharmaceutical, and food products. (source: American Heritage Dictionary)

 

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Last update: Oct 39, 2013; 4:58 p.m. LAH