lei gong teng (thunder god vine),
(in English and Chinese
and edited by:
Hing Kwok Chu
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of lei gong teng comes from the roots, leaves and flowers of the tripterygium
wilfordii Hook. f. It is collected during summer and autumn. Lei gong teng is
a deciduous climbing vine growing to 12 meters, with brown, angular, downy
twigs. The leaves are light green, smooth on top, and pale gray with light hairs
underneath. They have crenate margins and pointed apexes, and are
ovate to elliptic, 5-15 cm long, 2.5 - 7 cm wide. The scented hermaphroditic
(having male and female organs) flowers are small and whitish with five petals
and are about 9 mm across. The fruit is 3-winged, and brownish red, about 1.5
can grow in light (sandy), medium (loamy) and heavy (clay) soils. It can survive
in acid, neutral and basic (alkaline) soil. It can grow in semi-shade
(light woodland) or no shade. It requires moist soil.
wilfordii Hook. f.
Pron. in Korean:
Pron. in Cantonese
leoi4 gung1 tang4
Steps and Die" , "Intestine Breaking Plant"
southern part of mainland China, Taiwan, Burma
and very toxic
Actions & Indications:
anti-inflammation, kills worms, resolves toxins,
treating proteinuric renal disease, used as immunosuppressive
agent on autoimmune diseases.
wilforgine, wilforgine-B, wilfordine, wilfornine, wilfortrine, wilforttrine-D,
wilforzine[1-3], wilformine , wilfordinic acid, hyudroxywilfordic
acid ,wilfornine , neowilforine 
celacinnine, celafurine, celabenzine, celallocinnine [8-9]
triptofordinine A-1, A-2 , triptofordin D-1, D-2, E , triptofordin
A, B, C-1 C-2 , triptofordin F-1, F-2, F-3, F-4 
triptolide, tripdiolide, triptonide,[14-15], tripterolide.
triptolidenol [16-17], tripnolide , neotriptophenolide, triptophenolide
methyl ether , isoneotrip-tophenolide, hypolide methyl ether .
triptonoterpene, triptonoterpene methyl ether , triptonoterpenol
12-ydroxy-abieta-8, 11, 13 -trien-3-one, 11-hydroxy-14-methoxy-abieta-8,
11-hydroxy-14-methoxy-abieta-8, 11, 13-trien-3-one .
(1). wilforlide A, wilforlide B .
tritotriterpenoid lactone , tretotriterpenic acid A [25,26], tritotriterpenic
acid B , tritotriterpenic acid C , 3-epikatonic acid , polpunonic
acid, triptodihydroxy acid methyl ester , tripterine .
acid , salaspermic acid [29,32].
1,8-dihydroxy-4-hydroxymethyl anthraquinone .
dulcitol, glucose , tannin
on immune system
2. Effects on anti-inflammatory
Effects on anti-cancer
4. Effects on contraception
5. Effects on urinary system
6. Effects on anti-organism and worms
7. Other Effects
Anti rejection on transplants
8. Inside body
Effects of toxicity
purified from T. wilfordii may confer protection against the
FSGS (focal segmental gomerulosclerosis) factor.a
Research on Pharmacological Processes:
Modern Clinical Application:
of spinal cord
of the lungs
Psoriasis: Using water decoction
of lei gong teng and alcohol extract of lei gong teng:
contain 50 lei gong teng 50 g, and ji xue teng
50 g each. Take orally 50 ml, twice a day after meals.
30 days is
one therapy period.
taking alcohol extract: 116
taking water decoction: 77
that the alcohol extract was more effective than the water decoction. 
Toxicity and Side Effects:
Toxic reactions: dizziness, palpitation, weakness, nausea,
vomiting, stomach ache, diarrhea, pain in liver and kidney areas, bleeding
in the digestive tract, even respiration and circulation exhaustion and
of total blood cell counts (2)
type of illness: using lei gong teng tincture for external use can cause
mutation type of illness. (3)
Long -term use of lei gong teng could significantly decrease bone mineral
density of levels in female systemic lupus erythematosus (SLE)b
Long -term use of lei gong teng causes hair loss and malfunction of immune
6. Large dosages
and/or long term usage can be
Note: Focal segmental glomerulosclerosis
is scar tissue that forms in areas of the glomeruli of the kidneys that filter
harmful or unnecessary substances out of the body.
see picture on another site
See Chinese web page , submitted for writing competition sponsored by the
Education Department of ROC in Taiwan.
[n] If you need the complete bibliography in a hurry,
please email our
Research Librarian. There is a set up charge. Most of them are from sources
of Chinese writings.
(a). M. Sharma,
R. Sharma, XL Ge, R.S.Rdy, E.T.McCarthy, V. J. Savin, Medical College of Wisconsin,
Milwaukee, WI, U.S.A.
of dermatology, Huashan hospital, Shanghai Medical University, Shanghai 200040,
China (Huang L and Feng SF); Radiology Institute, Shanghai Medical University,
Shanghai 200040, China (Wang HF).
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Last update: May 21, 2011; 10:33 a.m.