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tian
hua fen, 天花粉 (in English and Chinese 中英文）
gua lou
gen 瓜蔞根
by: Joe Hing Kwok Chu
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Pharmaceutical name:
英文药名：
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Radix
Trichosanthis
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Biological name:
拉丁學名：
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Trichosanthes
kirilowii, Maxim, or Trichosanthes japonica, Regel.
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Pron. in
Japanese:
日語發音：
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tenkafun
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Pron. in
Korean:
韓語發音：
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chonhwabun
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Pron. in Cantonese:
粤語發音：
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tin1
faa1 fan2
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Other Names:
別名：
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tian hua fen originally called gua lou gen, also call ed hua fen.
原名括簍根，簡稱花粉
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Common
Name:
英文名：
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trichosanthes
root
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Distribution:
分佈：
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throughout
China, especially in Shandong, Hebei, Shanxi, Shaanxi
全中國，尤其是山東，
河北，山西，陕西。
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Properties
(characteristics)
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sweet, slightly
bitter, slightly cold
味甘微苦酸微寒
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Channels (meridians) entered:
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lung, stomach
歸肺、胃 經
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Actions & Indications:
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Clears lung
heat, dissolves phlegm, for cough with thick phlegm, rid of toxicity, expels
pus; for treatment of chlorion epithelioma, hydatidiform mole.
用於熱病煩渴， 肺熱
燥咳， 內熱消渴 ， 瘡瘍腫毒﹐治絨毛膜上皮癌及惡性葡萄胎。
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Modern Applications:
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hydatidiform tumor:
tian zao combination
formula: tian hua fen 60mg, ya zao jiao 25
mg ground into fine powder and put into capsules. Insert into vagina once
every 5 to 7 day. Treated 7 patients. Those had hydatiform tumors, 5 patients,
all healed. 2 patients with chorion-epothelioma (絨 癌 ) not effective. Using
tian zao combination formula and chemo therapy: 19 patients, healed 13,
ineffective 6.
Using tian zao combination formula and chemo therapy plus surgery: 65 patients,
healed 54, ineffective 11. [4]
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Medical
Function:
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1. Causes
miscarriage
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2. Effects
on immune system
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3. Anti
HIV
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4. Anti
tumor (immunotoxin,IT)
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5. Inhibits
synthesis of protein
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6. Others:
(1) affects blood sugar (2) anti bacteria
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7. Penetrating
parts of the body
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8. Toxicity
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Chemical ingredients:
化學成份：
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1. Protein
(蛋白質)
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Trichosanthin
(天花粉蛋白)with molecule weight of 24,000, and the
isoelectric point (等電點 ) is 9.4, is a simple protein that does not possess
phosphorous acid groups. Trichosanthin is being used clinically in inducing
delivery and it possesses effects of anti hydatiform tumor (葡萄胎 ) and
HIV.
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Karasurin
(堕胎蛋白)with molecule weight of 28,000, possesses the effects of abortion
in and inducing delivery, pregnant laboratory mice. It also inhibits
the imumme system
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α-momorcharin
(α-苦瓜素), molecule weight 29,000 and beta-momorcharin,
molecule weight 28,000, both contain 1.6% and 1.3% of neutral sugar.
Like trichosanthin, they also contain asparagic acid (天
冬氨酸)and glutamic acid (麩氨酸),
and do not contain cysteine (半胱氨酸 ).
2.
Polysaccharides
(多糖類)
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It is a
source of calories. It improves the imumme system, and possesses effects
of anti cancer and the toxic activities from the cells. The multi-sugar
consists of glucose(葡萄糖), fruitose (果糖), cerebrose (半乳糖 )， mannose (甘露糖 ), xylose
(木糖 ) and small amount of protein.
3. Plant Agglutinin
（ 凝集素 )
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TK I, TK
II, TK II
4. Enzyme
(酶)
5. Amino Acids
(氨基酸)
6. Others
(其他): β-sitosterol, α-spinasteryl-beta-D-glucoside,
α-spinasterol-
palmitate, ∆-7-stigmastenol-6'-(Z,z)-9,12-octadecadienoyl-beta-d-glucopyranoside,
More to be
loaded
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Dosage:
用量：
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9 - 15 g
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Samples
of formulae:
處方舉例：
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to be loaded
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Modern Research:
现代研究：
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to be loaded
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Cautions:
禁忌：
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not to be
used by pregnant women or in cases of
pixu (speen
deficient) or weixu (stomach deficient)。
Large dosages and/or long term usage can
be toxic to kidneys.
懷孕或脾
虛者忌用。大劑量或長期服用可能對
腎臟有毒。
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Hydatidiform tumor (Alternative
Names﹕
hydatidiform mole, trophoblastic
disease, gestational trophoblastic neoplasia)
Definition:
A hydatidiform tumor
occurs when a fetus is not able to fully form in the uterus and the fetal tissue
becomes a tumor.
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